HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 88098135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 70000063 | HCID 70000063 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 88098135 | HCID 88098135 | — |
Reaction Steps
A solution of (2R)-2-{[4-(4-(dimethoxymethyl)piperidin-1-yl)benzoyl]-amino}-butanedioic acid dibenzyl ester (0.215 g, 0.4 mol) in methylene chloride (10 mL) containing trifluoroacetic acid (0.165 mL, 2.0 mmol) was stirred at ambient temperature for 1 hour. The reaction was concentrated in vacuo to give the product which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06506901B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-ce997d76b958428b99e3b465b302a734 |
| Source note | uspto-grants-2003_01 |