Mannitol → Coenzyme A

HRID 1634857Notes

Reaction equation

HRID 1634857 reaction equation
CC(C)=O.[C@@H:5]1([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[O:42][C@H:14]([CH2:15][O:16][P:17]([O:20][P:21]([O:24][CH2:25][C:26]([C@H:29]([C:31]([NH:33][CH2:34][CH2:35][C:36]([NH:38][CH2:39][CH2:40][SH:41])=[O:37])=[O:32])[OH:30])([CH3:28])[CH3:27])([OH:23])=[O:22])([OH:19])=[O:18])[C@@H:8]([O:9][P:10]([OH:13])([OH:12])=[O:11])[C@H:6]1[OH:7].OC1[C@@H]([C@@H](O)CO)OC(=O)C=1O.P([O-])(O)(O)=O.[Na+].C(O)[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O>O>[CH3:28][C:26]([C@@H:29]([OH:30])[C:31]([NH:33][CH2:34][CH2:35][C:36]([NH:38][CH2:39][CH2:40][SH:41])=[O:37])=[O:32])([CH2:25][O:24][P:21]([O:20][P:17]([O:16][CH2:15][C@H:14]1[O:42][C@@H:5]([N:43]2[C:52]3[N:51]=[CH:50][N:49]=[C:47]([NH2:48])[C:46]=3[N:45]=[CH:44]2)[C@H:6]([OH:7])[C@@H:8]1[O:9][P:10]([OH:13])([OH:12])=[O:11])([OH:19])=[O:18])([OH:23])=[O:22])[CH3:27]

Participants

6

Reactant 4

HCID 6251MannitolHCID 23672064Monosodium phosphateHCID 54670067L-Ascorbic AcidHCID 86758803HCID 86758803, compound

Product 1

HCID 87642Coenzyme A

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

750 ml salt-free water were added to 500,000 units of CoA acetone powder, then 25 g Vitamin C, 25 g sodium dihydrogen phosphate and 25 g mannitol were added in turn, the mixture was stirred to dissolve and lyophilized.

Workup

  1. dissolutionto dissolve

Sources & evidence

ORD record
ord-0f1d064d047d41c4b85ae8859a7252c2
Source dataset
uspto-grants-2003_01
Patent number
US06509035B1

Reaction notes

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