Piperazine → HCID 12016332, compound

HRID 1634872Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=2)[CH2:16]Cl)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=2)[CH2:16][N:21]2[CH2:26][CH2:25][N:24]([CH2:16][C:15]3[CH:18]=[CH:19][CH:20]=[C:13]([C:5]4[CH:6]=[C:7]([O:11][CH3:12])[C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=4)[CH:14]=3)[CH2:23][CH2:22]2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10]

Participants

Reactant 2

HCID 4837Piperazine

HCID 120211573-(3,4,5-Trimethoxyphenyl)benzyl chloride

Product 1

HCID 12016332HCID 12016332, compound

Procedure

3-(3,4,5-Trimethoxyphenyl)benzyl chloride (120 mg) and piperazine (17 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record: ord-454bc2e05fcc49e59808e290b094e5ca
Source dataset: uspto-grants-2003_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06509329B1

Reaction notes

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