Piperazine → HCID 17963577, compound

HRID 1634876Notes

Reaction equation

HRID 1634876 reaction equation
Cl[CH2:2][C:3]1[C:4]([C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)=[N:5][CH:6]=[CH:7][CH:8]=1.[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:20][O:19][C:11]1[CH:10]=[C:9]([C:4]2[C:3]([CH2:2][N:21]3[CH2:26][CH2:25][N:24]([CH2:2][C:3]4[C:4]([C:9]5[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=5)=[N:5][CH:6]=[CH:7][CH:8]=4)[CH2:23][CH2:22]3)=[CH:8][CH:7]=[CH:6][N:5]=2)[CH:14]=[C:13]([O:15][CH3:16])[C:12]=1[O:17][CH3:18]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 120431463-Chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine

Product 1

HCID 17963577HCID 17963577, compound

Procedure

3-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridine (241 mg) and piperazine (35 mg) were reacted in the same manner as in Example 1 to obtain the title compound as a free base.

Sources & evidence

ORD record
ord-f6d4cb8e3a7048ef8fcda99b76526b28
Source dataset
uspto-grants-2003_01
Patent number
US06509329B1

Reaction notes

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