Piperazine → HCID 18674985, compound

HRID 1634889Notes

Reaction equation

Cl[CH2:2][C:3]1[CH:8]=[C:7]([C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)[CH:6]=[CH:5][N:4]=1.[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:20][O:19][C:11]1[CH:10]=[C:9]([C:7]2[CH:6]=[CH:5][N:4]=[C:3]([CH2:2][N:21]3[CH2:26][CH2:25][N:24]([CH2:2][C:3]4[CH:8]=[C:7]([C:9]5[CH:10]=[C:11]([O:19][CH3:20])[C:12]([O:17][CH3:18])=[C:13]([O:15][CH3:16])[CH:14]=5)[CH:6]=[CH:5][N:4]=4)[CH2:23][CH2:22]3)[CH:8]=2)[CH:14]=[C:13]([O:15][CH3:16])[C:12]=1[O:17][CH3:18]

Participants

Reactant 2

HCID 4837Piperazine

HCID 18674973HCID 18674973, compound

Product 1

HCID 18674985HCID 18674985, compound

Procedure

2-Chloromethyl-4-(3,4,5-trimethoxyphenyl)pyridine (195 mg) and piperazine (28 mg) were reacted in the same manner as in Example 1 to obtain the title compound.

Sources & evidence

ORD record: ord-09aff1677b0742889e65a3a35ab16917
Source dataset: uspto-grants-2003_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06509329B1

Reaction notes

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