Dichloromethane → N-(2-aminophenyl)-4-[3-oxo-3-(2-pyridin-3-ylethylamino)prop-1-enyl]benzamide

HRID 163508Notes

Reaction equation

HRID 163508 reaction equation
[Cl:44][CH2:45][Cl:46].[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43].[n:1]1[cH:2][c:3]([CH2:7][CH2:8][NH:9][C:10](=[O:11])[CH:12]=[CH:13][c:14]2[cH:15][cH:16][c:17]([C:18](=[O:19])[NH:20][c:21]3[c:22]([NH:27][C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[cH:23][cH:24][cH:25][cH:26]3)[cH:35][cH:36]2)[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH2:7][CH2:8][NH:9][C:10](=[O:11])[CH:12]=[CH:13][c:14]2[cH:15][cH:16][c:17]([C:18](=[O:19])[NH:20][c:21]3[c:22]([NH2:27])[cH:23][cH:24][cH:25][cH:26]3)[cH:35][cH:36]2)[cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86602772t-Butyl (2-{4-[2-(2-pyridin-3-yl-ethylcarbamoyl)vinyl]-benzoylamino}-phenyl)-carbamate

Product 1

HCID 68981353N-(2-aminophenyl)-4-[3-oxo-3-(2-pyridin-3-ylethylamino)prop-1-enyl]benzamide

Sources & evidence

ORD record
ord-5af5c8d9c468474a854e8b78e37c7f06
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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