Methyl bromoacetate → HCID 12052441, compound

HRID 1635127Notes

Reaction equation

[CH2:1]([C:8]1[S:12][C:11]2[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=2[C:9]=1[C:17]([C:19]1[CH:24]=[C:23]([Br:25])[C:22]([OH:26])=[C:21]([Br:27])[CH:20]=1)=[O:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:29][C:30]([O:32]C)=[O:31]>>[CH2:1]([C:8]1[S:12][C:11]2[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=2[C:9]=1[C:17]([C:19]1[CH:20]=[C:21]([Br:27])[C:22]([O:26][CH2:29][C:30]([OH:32])=[O:31])=[C:23]([Br:25])[CH:24]=1)=[O:18])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 60984Methyl bromoacetate

HCID 10553492HCID 10553492, compound

Product 1

HCID 12052441HCID 12052441, compound

Procedure

This compound was prepared from (2-benzyl-benzo[b]thiophen-3-yl)-(3,5-dibromo-4-hydroxy-phenyl)-methanone and methyl bromoacetate in substantially the same manner, as described in Example 20, and was obtained as an off-white solid, mp 162-163° C., MS m/e 558 (M)+; Analysis for: C24H16Br2O4S Calc'd: C, 51.45; H, 2.88 Found: C, 51.15; H, 2.71

Workup

customwas obtained as an off-white solid, mp 162-163° C., MS m/e 558 (M)+

Sources & evidence

ORD record: ord-b95520f2d1954f80a63475c7cb9dba1d
Source dataset: uspto-grants-2003_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06509360B1

Reaction notes

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