HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22224850, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | 3-Oxo-3-(pyridin-4-yl)propanoic acid | HCID 15511204 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 22224850 | HCID 22224850 | — |
Reaction Steps
Prepared from 3-oxo-3-pyridin-4-yl-propionic acid [prepared from 4-acetylpyridine, magnesium methylcarbonate and CO2 in DMF at 120° C. according to Journal of Antibiotics 1978, 31, 1245] by treatment with acetone, TFA and TFAA according to general procedure J (method b). Obtained as a white solid (1.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06509328B1 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-dc62d72163c34715a26252ad541ef677 |
| Source note | uspto-grants-2003_01 |