1,2-Dichloroethane → trans-{4-[2-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH:15]=[O:16])[CH2:12][CH2:13]1)=[O:17].[C:33]([OH:34])(=[O:35])[CH3:36].[Cl:42][CH2:43][CH2:44][Cl:45].[N:18]1([c:24]2[n:25][cH:26][cH:27][c:28]3[c:29]2[cH:30][cH:31][s:32]3)[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[Na+:41].[O-:37][C:38]([OH:39])=[O:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][N:21]2[CH2:20][CH2:19][N:18]([c:24]3[n:25][cH:26][cH:27][c:28]4[c:29]3[cH:30][cH:31][s:32]4)[CH2:23][CH2:22]2)[CH2:12][CH2:13]1)=[O:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d6edea6a340e40b69ba0d2ba971fcaec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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