Hydrazine hydrate (1:1) → 2-(3,5-Dimethylmorpholino)ethylamine

HRID 1635645Notes

Reaction equation

HRID 1635645 reaction equation
[CH3:1][CH:2]1[N:7]([CH2:8][CH2:9][N:10]2C(=O)C3C(=CC=CC=3)C2=O)[CH:6]([CH3:21])[CH2:5][O:4][CH2:3]1.O.NN>>[CH3:21][CH:6]1[N:7]([CH2:8][CH2:9][NH2:10])[CH:2]([CH3:1])[CH2:3][O:4][CH2:5]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 234412322-[2-(3,5-dimethylmorpholino)ethyl]-1H-isoindole-1,3(2H)-dione

Product 1

HCID 120961382-(3,5-Dimethylmorpholino)ethylamine

Procedure

The title compound was prepared by a similar method to Preparation 7 from 2-[2-(3,5-dimethylmorpholino)ethyl]-1H-isoindole-1,3(2H)-dione [see Preparation 11] and hydrazine hydrate, to afford 2-(3,5-dimethylmorpholino)ethylamine as a white solid.

Sources & evidence

ORD record
ord-19f5a80c04bf421d92e92b662798ec4d
Source dataset
uspto-grants-2003_01
Patent number
US06509464B1

Reaction notes

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