HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethanol → 2-(2,2,2-Trifluoroethoxy)ethan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Reactant | Ethylene carbonate | HCID 7303 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Product | 2-(2,2,2-Trifluoroethoxy)ethan-1-ol | HCID 255854 | — |
Reaction Steps
A mixture of 36 ml (0.50 mol) of 2,2,2-trifluoroethanol, 66 g (0.75 mol) of ethylene carbonate and 70 ml (0.50 mol) of triethylamine was heated to reflux for 16 h. Distillation of the reaction mixture through a Vigreux column at normal pressure yielded the title compound as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06511989B2 |
| Source dataset | uspto-grants-2003_01 |
| ORD ID | ord-49bb9723537d415885256fe9d7082d08 |
| Source note | uspto-grants-2003_01 |