Methylhydrazine → HCID 9907359, compound

HRID 1635839Notes

Reaction equation

HRID 1635839 reaction equation
CN([CH:4]=[N:5][C:6](=O)[C:7]1[CH:12]=[CH:11][C:10]([C:13]([N:15]2[C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=3[CH2:19][N:18]3[CH:26]=[CH:27][CH:28]=[C:17]3[CH2:16]2)=[O:14])=[CH:9][CH:8]=1)C.[CH3:30][NH:31][NH2:32]>C(O)(=O)C>[CH3:30][N:31]1[C:6]([C:7]2[CH:8]=[CH:9][C:10]([C:13]([N:15]3[C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[CH2:19][N:18]4[CH:26]=[CH:27][CH:28]=[C:17]4[CH2:16]3)=[O:14])=[CH:11][CH:12]=2)=[N:5][CH:4]=[N:32]1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 22605454HCID 22605454, compound

Product 1

HCID 9907359HCID 9907359, compoundYield 6.7%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In the same manner as Example 48, employing N-(dimethylaminomethylene)-4-(5H,11H-pyrrolo[2,1-c][1,4]benzodiazepine-10-carbonyl)-benzamide (1.56 g) from Example 46 in glacial acetic acid (75 ml) and methylhydrazine (0.32 g), the title compound (0.10 g) was obtained as a solid, m.p. 155-158° C.; MS, m/z: 369 (M)+.

Sources & evidence

ORD record
ord-2bffeb512092498480c9684c29ca4b9e
Source dataset
uspto-grants-2003_01
Patent number
US06511974B1

Reaction notes

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