Trifluoroacetic acid → HCID 23557283, compound

Participants

Reaction Steps

To a stirred solution of 40 (200 mg, 0.59 mmol) in CH2Cl2 (10 mL) was added TFA (1 mL). The reaction was allowed to proceed overnight. Volatiles were removed under reduced pressure to leave 41 as a white solid (112 mg, 0.49 mmol, 83%). 1H-NMR (CD3OD, 400 MHz) δ 7.11 (dd, 1H), 6.33 (dd, 1H), 6.16 (m, 1H), 5.81 (d, 1H), 3.76 (s, 3H), 3.15 (t, 1H), 2.70 (t, 2H).

Provenance & Evidence