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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 163592Generated: October 30, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({5-[(1,1-dioxidothiomorpholin-4-yl)methyl]-6-fluoropyridin-2-yl}amino)thiophene-3-carboxamide

https://huagongshe.com/reaction/163592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant4-[(6-Chloro-2-fluoropyridin-3-yl)methyl]thiomorpholine 1,1-dioxideHCID 59525716—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({5-[(1,1-dioxidothiomorpholin-4-yl)methyl]-6-fluoropyridin-2-yl}amino)thiophene-3-carboxamideHCID 68670673—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-97a3508536e748339cf1aaf0d3db8771
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)