Lithium Hydroxide → HCID 18674669, compound

Participants

Reaction Steps

Ethyl 6-(9H-carbazol-2-yloxy)-hexanoate (270 mg, 0.8 mmol) and 1 N aqueous lithium hydroxide (2 ml, 2 mmol) in 15 ml methanol was heated to reflux for 1h. The solvent was removed, the residue was acidified by 1 ml 2N aqueous hydrochloric acid. The precipitate was collected to give 6-(9H-carbazol-2-yloxy)-hexanoic acid (230 mg, 93%) as a colorless solid. MS (M−H+)296.

Provenance & Evidence