Cyclohexylamine → HCID 18468886, compound

HRID 1636212Notes

Reaction equation

HRID 1636212 reaction equation
Cl[Si:2]([CH3:17])([CH3:16])[CH:3]1[C:14]2[C:6](=[CH:7][C:8]3[CH2:9][CH2:10][CH2:11][C:12]=3[CH:13]=2)[CH:5]=[C:4]1[CH3:15].CCN(CC)CC.[CH:25]1([NH2:31])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>CCCCCC>[CH:25]1([NH:31][Si:2]([CH3:17])([CH3:16])[CH:3]2[C:14]3[C:6](=[CH:7][C:8]4[CH2:9][CH2:10][CH2:11][C:12]=4[CH:13]=3)[CH:5]=[C:4]2[CH3:15])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1

Participants

5

Reactant 3

HCID 7965CyclohexylamineHCID 8471TriethylamineHCID 18468888HCID 18468888, compound

Product 1

HCID 18468886HCID 18468886, compoundYield 94.3%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Chlorodimethyl(1,5,6,7-tetrahydro-2-methyl-s-indacen-1-yl) silane (5.67 g, 0.0216 moles) was stirred in hexane (50 mL) as NEt3 (2.18 g, 0.0216 moles) and cyclohexylamine (2.13 g, 0.0216 moles) were added. This mixture was allowed to stir 16 hours. After the reaction period the mixture was filtered and the volatiles removed resulting in the isolation of the desired product as a yellow oil (6.62 g, 94.3 percent).

Workup

  1. additionwere added
  2. customAfter the reaction period the mixture
  3. filtrationwas filtered
  4. customthe volatiles removed

Sources & evidence

ORD record
ord-dcac4f66ca344d8faf7ca27e9b993a79
Source dataset
uspto-grants-2000_03
Patent number
US06034022

Reaction notes

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