Hydrochloric Acid → HCID 19350833, compound

Participants

Reaction Steps

5,5-Dimethoxy-2-hydroxymethylpentanol (2.87 g) was dissolved in tetrahydrofuran, and 1N hydrochloric acid (0.1 ml) was added dropwise thereto, and then the mixture stirred at room for 4 hours. After concentrating the reaction mixture, the residue was purified on a silica gel column (eluent: chloroform/methanol=20/1) to obtain the desired product (2.07 g, 88%) as pale yellow oil.

Provenance & Evidence