Hydrochloric Acid → HCID 19350833, compound

HRID 1636299Notes

Reaction equation

HRID 1636299 reaction equation
C[O:2][CH:3]([O:11][CH3:12])[CH2:4][CH2:5][CH:6]([CH2:9]O)[CH2:7][OH:8].Cl>O1CCCC1>[CH3:12][O:11][CH:3]1[CH2:4][CH2:5][CH:6]([CH2:7][OH:8])[CH2:9][O:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19350817HCID 19350817, compound

Product 1

HCID 19350833HCID 19350833, compoundYield 88%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

5,5-Dimethoxy-2-hydroxymethylpentanol (2.87 g) was dissolved in tetrahydrofuran, and 1N hydrochloric acid (0.1 ml) was added dropwise thereto, and then the mixture stirred at room for 4 hours. After concentrating the reaction mixture, the residue was purified on a silica gel column (eluent: chloroform/methanol=20/1) to obtain the desired product (2.07 g, 88%) as pale yellow oil.

Workup

  1. concentrationAfter concentrating the reaction mixture
  2. customthe residue was purified on a silica gel column (eluent: chloroform/methanol=20/1)

Sources & evidence

ORD record
ord-fae2bc3e1f834d9b99086459a14d91fb
Source dataset
uspto-grants-2000_03
Patent number
US06034087

Reaction notes

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