3-Pyridinecarboxaldehyde → HCID 53771911, compound

HRID 1636312Notes

Reaction equation

HRID 1636312 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=O)[CH:2]=1.[NH2:9][N:10]1[CH2:15][CH:14]([CH3:16])[NH:13][NH:12][C:11]1=[O:17]>S(=O)(=O)(O)O.C(O)C>[CH3:16][CH:14]1[NH:13][NH:12][C:11](=[O:17])[N:10]([N:9]=[CH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[CH2:15]1

Participants

5

Reactant 2

HCID 103713-PyridinecarboxaldehydeHCID 19350727HCID 19350727, compound

Product 1

HCID 53771911HCID 53771911, compound

Reagents, catalysts & solvents 2

HCID 1118Sulfuric AcidCatalystHCID 702EthanolSolvent

Procedure

2.2 g of pyridine-3-carbaldehyde and 2 drops of sulfuric acid are added to a solution of 3 g of 4-amino-6-methyl-3-oxo-1,4,5,6-tetrahydro-1,2,4-triazine in 30 ml of ethanol. The reaction mixture is then maintained under reflux for 90 minutes and then the resulting suspension is cooled to 20°, filtered and dried. 4.1 g of the title compound having a melting point of 235-237° are obtained.

Workup

  1. temperatureThe reaction mixture is then maintained
  2. temperatureunder reflux for 90 minutes
  3. temperaturethe resulting suspension is cooled to 20°
  4. filtrationfiltered
  5. customdried
  6. customare obtained

Sources & evidence

ORD record
ord-042b9df121e94aa7bb3be4942e9ce97a
Source dataset
uspto-grants-2000_03
Patent number
US06034083

Reaction notes

Loading…