Hydrazine hydrate (1:1) → HCID 19350729, compound

HRID 1636313Notes

Reaction equation

HRID 1636313 reaction equation
O.NN.[CH3:4][N:5]1[C:9]([CH3:10])=[CH:8][N:7]([N:11]=CC2C=NC=CC=2)[C:6]1=[O:19]>CO>[NH2:11][N:7]1[CH:8]=[C:9]([CH3:10])[N:5]([CH3:4])[C:6]1=[O:19]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 53902487HCID 53902487, compound

Product 1

HCID 19350729HCID 19350729, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2 g of hydrazine hydrate are added to a solution of 2 g of 3,4-dimethyl-1-(pyridin-3-ylmethyleneamino)-2,3-dihydroimidazol-2-one in 12 ml of methanol and the suspension is boiled under reflux for 6 hours, then concentrated by evaporation and chromatographed on silica gel. 1 g of pyridine-3-carbaldehyde hydrazone and 0.7 g of the title compound having a melting point of 115-119° are thus obtained.

Workup

  1. temperatureunder reflux for 6 hours
  2. concentrationconcentrated by evaporation
  3. customchromatographed on silica gel
  4. customare thus obtained

Sources & evidence

ORD record
ord-abee66a10a284f999a4460b843852671
Source dataset
uspto-grants-2000_03
Patent number
US06034083

Reaction notes

Loading…