HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-[(2-methoxyanilino)methylidene]-5-methyl-2-phenylpyrazol-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Mci-186 | HCID 4021 | — |
| Reactant | 2-Methoxyaniline | HCID 7000 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[(2-methoxyanilino)methylidene]-5-methyl-2-phenylpyrazol-3-one | HCID 178489588 | — |
Reaction Steps
5-Methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 2 g trimethylorthoformiate (188 ml) and o-anisidin (1.29 ml) are heated swith glacial acetic acid (5 ml) to 70° C. for 2 hours. After the reaction mixture cools down, methanol is added. The precipitate is collected and recrystallized in ethylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06034099 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-a1630f581d4c42ee937e13720b101adb |
| Source note | uspto-grants-2000_03 |