Benzene → 1,5,6,7-tetrahydro-1-(4-bromophenyl]-3-(morpholin-4-yl)-2H-azepin-2-one

HRID 163644Notes

Reaction equation

HRID 163644 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:16])[CH2:10][C:11](=[O:15])[CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1.[CH2:17]1[CH2:18][O:19][CH2:20][CH2:21][NH:22]1.[c:23]1([CH3:24])[cH:25][cH:26][c:27]([S:28]([OH:29])(=[O:30])=[O:31])[cH:32][cH:33]1.[cH:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[C:9](=[O:16])[C:10]([N:22]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)=[CH:11][CH2:12][CH2:13][CH2:14]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 241BenzeneHCID 6101p-Toluenesulfonic acidHCID 8083MorpholineHCID 22566235HCID 22566235, compound

Product 1

HCID 225662551,5,6,7-tetrahydro-1-(4-bromophenyl]-3-(morpholin-4-yl)-2H-azepin-2-one

Sources & evidence

ORD record
ord-011806b725b34a6288e390ff6fd8725a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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