Isopropylamine → HCID 19352247, compound

Participants

Reaction Steps

A mixture of γ-phenyl-γ-butyrolactone (10.0 g, 61.7 mmol) and isopropylamine (50 ml, 587 mmol) was stirred at room temperature for approximately 26 hours. The solvent was removed under reduced pressure to give 4-hydroxy-N-isopropyl-4-phenyl-butyramide (13.71 g, 100%) as a yellow solid, mp 131-135° C.

Provenance & Evidence