HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 19349446, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 19349435 | HCID 19349435 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19349446 | HCID 19349446 | — |
Reaction Steps
A solution of the product from Example 27 (1 g) and thionyl chloride (0.4 ml) in dichloromethane (5 ml) was heated under reflux for 0.5 h, then evaporated to dryness under reduced pressure, to give 2-[3-chloromethyl-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile hydrochloride, mp. 189°-190° after trituration with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE036617 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-3a69181eeb584b4ebfda81cb5e3f0499 |
| Source note | uspto-grants-2000_03 |