HCID 19349789, compound → HCID 19349785, compound

HRID 1636889Notes

Reaction equation

HRID 1636889 reaction equation
[CH3:1][N:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:8]=[C:9]([N+:13]([O-])=O)[CH:10]=[CH:11][CH:12]=2)[NH:3]1.[H][H]>[Pt]=O.C(O)C>[CH3:1][N:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:8]=[C:9]([CH:10]=[CH:11][CH:12]=2)[NH2:13])[NH:3]1

Participants

5

Reactant 2

HCID 19349789HCID 19349789, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19349785HCID 19349785, compoundYield 93%

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

The nitro group is reduced as follows: To a 250 ml Parr bottle are added 800 mg (3.9 mmol) of 3-(1-methyltetrazol-3-yl)nitrobenzene, 200 mg platinum oxide, and 75 ml ethanol. The reaction is pressurized with 45 p.s.i. hydrogen for 1 hour, then catalyst removed by filtration, and the solvent evaporated to afford 635 mg (93.0%) of a white solid, mp 93°-95° C.

Workup

  1. customcatalyst removed by filtration
  2. customthe solvent evaporated

Sources & evidence

ORD record
ord-caae2ba83f554ab5b44e375bebeef6b7
Source dataset
uspto-grants-2000_03
Patent number
US06037345

Reaction notes

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