反应详情

Z-1-[4-(2-benzyloxyethoxy)-phenyl]-4-chloro-1,2-diphenyl-but-1-ene (36 g, 0.08 mol) was dissolved in the mixture of ethyl acetate (350 ml) and ethanol (350 ml). Palladium on carbon (5%, 0.28 g) was added and the solution was flushed with hydrogen gas until there was not any starting compound left (thin layer chromatography). Palladium on carbon was filtered off through siliceous earth and the filtrate was evaporated. The residue was crystallized from the mixture of ethanol (155 ml) and water (65 ml). Yield 20 g.

1. customthe solution was flushed with hydrogen gas until there
2. waitleft (thin layer chromatography)
3. filtrationPalladium on carbon was filtered off through siliceous earth
4. customthe filtrate was evaporated
5. customThe residue was crystallized from the mixture of ethanol (155 ml) and water (65 ml)