HCID 53837207, compound → 2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methylacetamide

HRID 1637011Notes

Reaction equation

HRID 1637011 reaction equation
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12](=[N:16][O:17][CH3:18])[C:13]([NH2:15])=[O:14])(=O)C.[CH3:19]N.CO>CO>[OH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[C:12](=[N:16][O:17][CH3:18])[C:13]([NH:15][CH3:19])=[O:14]

Participants

4

Reactant 2

HCID 53837207HCID 53837207, compoundHCID 57454252Monomethylamine methanol

Product 1

HCID 544725602-(2-hydroxymethylphenyl)-2-methoxyimino-N-methylacetamide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 2-(2-acetoxymethylphenyl)-2-methoxyiminoacetamide (194 mg, E/Z≠79/21), methanol (3.0 ml) and a 40% methylamine/methanol solution (1.0 ml) was stirred at 40° C. for 3 hours. After the mixture was ice-cooled, the solvent was evaporated under reduced pressure to obtain the crude product (203 mg, E/Z≠91/9) of the title compound.

Workup

  1. temperaturecooled
  2. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-ebcb612826b64e44832bab593028e4f1
Source dataset
uspto-grants-2000_03
Patent number
US06037495

Reaction notes

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