Benzyl Alcohol → Benzophenone

HRID 1637066Notes

Reaction equation

HRID 1637066 reaction equation
C(O)C1C=CC=CC=1.[CH:9]([OH:22])([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.ON1C(=O)C2=CC=CC=C2C1=O>>[C:9]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)(=[O:22])[CH3:16].[C:9]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:22])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 244Benzyl AlcoholHCID 7037BenzhydrolHCID 10665N-Hydroxyphthalimide

Product 2

HCID 3102BenzophenoneHCID 7410Acetophenone

Procedure

In page 762 of the "Lecture Draft II" (1994) of 67th Spring Annual Meeting of Chemical Society of Japan, it is reported that oxidation of an alcohol such as benzyl alcohol or benzhydrol with air using vanadomolybdophosphoriate and N-hydroxyphthalimide provides a ketone such as acetophenone or benzophenone in a high yield, and that oxidation of fluorene or adamantane with oxygen using N-hydroxyphthalimide gives a corresponding adamantanol or fluorenone.

Sources & evidence

ORD record
ord-b00491ef4306478c98fe64ec3ab21d62
Source dataset
uspto-grants-2000_03
Patent number
US06037507

Reaction notes

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