Isobutane → tert-Butanol

HRID 1637068Notes

Reaction equation

HRID 1637068 reaction equation
[CH3:1][CH:2]([CH3:4])[CH3:3].[OH:5]N1C(=O)C2=CC=CC=C2C1=O>C(#N)C1C=CC=CC=1>[C:2]([OH:5])([CH3:4])([CH3:3])[CH3:1].[CH3:1][C:2]([CH3:4])=[O:5]

Participants

5

Reactant 2

HCID 6360IsobutaneHCID 10665N-Hydroxyphthalimide

Product 2

HCID 180AcetoneYield 14%HCID 6386tert-ButanolYield 81%

Reagents, catalysts & solvents 1

HCID 7505BenzonitrileSolvent

Procedure

To benzonitrile was added 5 mmol of isobutane, 0.5 mmol of N-hydroxyphthalimide (NHPI) and 0.0125 mmol of cobalt acetate Co(OAc)2, and the resultant mixture was stirred under an air atmosphere at a pressure of 10 atm and at a temperature of 100° C. for 8 hours. The products in the reaction mixture were analyzed by gas chromatography, and, as a result, t-butanol (yield 81%) and acetone (yield 14%) were formed.

Sources & evidence

ORD record
ord-a5a17b9165564dcd97c75eb871c05936
Source dataset
uspto-grants-2000_03
Patent number
US06037507

Reaction notes

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