HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-(3,5-Dimethylbenzoyl)-hexahydro-7-phenyl-1,4-diazepin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3,5-Dimethylbenzoyl Chloride | HCID 81088 | — |
| Reactant | 7-Phenyl-1,4-diazepan-5-one | HCID 13048235 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(3,5-Dimethylbenzoyl)-hexahydro-7-phenyl-1,4-diazepin-5-one | HCID 19347931 | 98.5% |
Reaction Steps
3.0 g hexahydro-7-phenyl-1,4-diazepin-5-one (for preparation see Example 1C)) in 40 ml dichloromethane were reacted with 4.0 g triethylamine and 2.9 g 3,5-dimethylbenzoyl chloride according to the method given above in Example 1F). 5.01 g amorphous 1-(3,5-dimethylbenzoyl)-hexahydro-7-phenyl-1,4-diazepin-5-one were obtained, which was reacted without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06040303 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-a34db4285099472a9021b91d519a1d21 |
| Source note | uspto-grants-2000_03 |