Benzonitrile → HCID 178418369, compound

HRID 1637359Notes

Reaction equation

HRID 1637359 reaction equation
[C:1](#[N:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N-:9]=[N+:10]=[N-:11].[Na+].Cl.C(NCC)C>C1(C)C=CC=CC=1>[C:2]1([C:1]2[NH:11][N:10]=[N:9][N:8]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 7505BenzonitrileHCID 33557Sodium AzideHCID 10197650Diethylammonium chloride

Product 1

HCID 178418369HCID 178418369, compoundYield 96%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Into the same device as used in Example 1 were placed 5.16 g (0.050 mole) of benzonitrile, 4.23 g (0.065 mole) of sodium azide, 7.13 g (0.065 mole) of diethylamine hydrochloride and 52 ml of toluene. The mixture was reacted for 8 hours in the same manner as in Example 1, giving 7.02 g (0.048 mole) of 5-phenyl-1H-tetrazole (yield 96.0% based on benzonitrile).

Workup

  1. customThe mixture was reacted for 8 hours in the same manner as in Example 1

Sources & evidence

ORD record
ord-edc427461db14c30895478891ca22d71
Source dataset
uspto-grants-2000_03
Patent number
US06040454

Reaction notes

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