Carbonochloridic acid, 4-methoxyphenyl ester → 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(4-methoxyphenoxy)carbonyl]hydrazine

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Reaction Steps

1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(4-methoxyphenoxy)carbonyl]hydrazine (compound 10g) was prepared by reacting compound 2 with 4-methoxyphenyl chloroformate using a procedure similar to the one employed for compound 10d. The product was recrystallized from ethanol, and the yield was about 30.0% by weight. The Mp of the product was approximately 119-121° C. 1H NMR (CDCl3): δ 7.1 and 6.9 (4H, 2d, aromatic H), 3.6-4.2 (4H, m, CH2CH2Cl), 3.8 (3H, s, OCH3), 3.5 and 3.2 (6H, 2s, 2 CH3SO2).

Provenance & Evidence