1-Methylimidazole → HCID 86755252, compound

HRID 1637398Notes

Reaction equation

HRID 1637398 reaction equation
[CH2:1]([O:4][N:5]([O:13][CH2:14][CH2:15][CH3:16])[C:6]1[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=1)[CH2:2][CH3:3].[C:17]([O:20]C(=O)C)(=[O:19])[CH3:18].CN1C=CN=C1>>[C:17]([OH:20])(=[O:19])[CH3:18].[C:17]([OH:20])(=[O:19])[CH3:18].[CH2:14]([O:13][N:5]([O:4][CH2:1][CH2:2][CH3:3])[C:6]1[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=1)[CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 13901-MethylimidazoleHCID 7918Acetic AnhydrideHCID 19349301HCID 19349301, compound

Product 1

HCID 86755252HCID 86755252, compound

Conditions

Temperature
135 °C

Procedure

22.5 parts of N,N-dipropoxy-m-aminophenol were charged to a reactor vessel followed by 22.0 parts of-acetic anhydride and 0.5 parts of 1-methylimidazole. The mixture was then heated to about 130 to 140° C. and held for 3 hours. The acetic acid and excess anhydride were then distilled out at a temperature from 130 to 140° C. leaving the N,N-dipropoxy-m-aminophenol diacetate product.

Workup

  1. distillationThe acetic acid and excess anhydride were then distilled out at a temperature from 130 to 140° C.

Sources & evidence

ORD record
ord-cd8e83f54dfb4007a5fd704fcefb4373
Source dataset
uspto-grants-2000_03
Patent number
US06040482

Reaction notes

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