1,3-Dibromopropane → HCID 19348520, compound

HRID 1637559Notes

Reaction equation

HRID 1637559 reaction equation
[Cl:1][C:2]1[C:3]([OH:20])=[CH:4][C:5]([O:18][CH3:19])=[C:6]([CH:8]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:7]=1.[Br:21][CH2:22][CH2:23][CH2:24]Br>>[Cl:1][C:2]1[C:3]([O:20][CH2:24][CH2:23][CH2:22][Br:21])=[CH:4][C:5]([O:18][CH3:19])=[C:6]([CH:8]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:9][C:10]([O:12][CH3:13])=[O:11])[CH:7]=1

Participants

3

Reactant 2

HCID 80011,3-DibromopropaneHCID 19348793HCID 19348793, compound

Product 1

HCID 19348520HCID 19348520, compound

Procedure

Following a similar procedure to that described in Preparation 45A(i), but using methyl 3-(5-chloro-4-hydroxy-2-methoxyphenyl)heptanoate (prepared as described in Preparation 56B) and 1,3-dibromopropane, methyl 3-[5-chloro-2-methoxy-4-(3-bromopropoxy)phenyl]heptanoate was obtained as an oily substance.

Workup

  1. customthat described in Preparation 45A(i)

Sources & evidence

ORD record
ord-3e45f0753bf04834a182f7815948d90f
Source dataset
uspto-grants-2000_03
Patent number
US06040339

Reaction notes

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