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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1637634Generated: November 1, 2026

6-[3-(2-Chloromethyl-3-methylpyridin-4-ylsulfanyl)propylsulfanyl]-3-nitroimidazo[1,2-b]pyridazine → HCID 178503102, compound

https://huagongshe.com/reaction/1637634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-[3-(2-Chloromethyl-3-methylpyridin-4-ylsulfanyl)propylsulfanyl]-3-nitroimidazo[1,2-b]pyridazineHCID 18799383—
ReactantHCID 178503100HCID 178503100—
SolventIsopropanolHCID 3776—
ProductHCID 178503102HCID 178503102145.5%

Reaction Steps

0.79 g (1.93 mmol) of 6-[3-(2-chloromethyl-3-methylpyridin-4-ylsulfanyl)propylsulfanyl]-3-nitro-imidazo[1,2-b]pyridazine and 0.41 g (1.1 mmol) of 6-methylsulfanyl-1H-benzoimidazole-2-thiol in 35 ml of isopropanol are reacted as described in Example 2. 0.97 g (97%) of the title compound of m.p. 193-195° C. is isolated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06043242
Source datasetuspto-grants-2000_03
ORD IDord-f5b4d617ec5e4fc48528bdfb22ddcf50
Source noteuspto-grants-2000_03