HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 70272534, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 6-Chloro-3-nitro-imidazo(1,2-b)pyridazine | HCID 10535981 | — |
| Reactant | HCID 18799398 | HCID 18799398 | — |
| Product | HCID 70272534 | HCID 70272534 | — |
Reaction Steps
Starting from 3-{[2-(1H-benzimidazol-2-ylsulfanylmethyl)-3-chloropyridin-4-yl]-methylamino}-propan-1-ol (3.0 g, 8.2 mmol) (see example D2.), 6-chloro-3-nitro-imidazo[1,2-b]pyridazine (1.72 g, 8.7 mmol) and sodium hydride (0.62 g 80% strength suspension) the title compound is prepared and purified according to the procedure given for example 27. Yield: 1.95 g, (42%). M.p. 202-03° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043242 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-905f6802cec0431682229edd12ac4407 |
| Source note | uspto-grants-2000_03 |