HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 492870, compound → HCID 470504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 492870 | HCID 492870 | — |
| Reactant | HCID 86755259 | HCID 86755259 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 470504 | HCID 470504 | — |
Reaction Steps
6-chloro-2-(2-naphthylmethyl)thio-4-pyrimidine carbonitrile (Cpd 276; 60 mg, 3.07 mmol) was stirred in THF/NH4OH (1:1, 15 ml) at 22° C. for 6 hrs. The reaction was diluted with ethyl acetate, washed with brine, dried with MgSO4, then concentrated in vacuo: 871 mg (2.97 mmol, 97%), mp 154-155° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043248 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-07ed5b93d9704a5589eeab7611f40f9a |
| Source note | uspto-grants-2000_03 |