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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1637869Generated: October 31, 2026

Tryptamine → HCID 18363100, compound

https://huagongshe.com/reaction/1637869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTryptamineHCID 1150—
ReactantTrifluoroacetic acidHCID 6422—
Reactantp-(Trifluoromethoxy)benzaldehydeHCID 69573—
ProductHCID 18363100HCID 1836310038.5%

Reaction Steps

This product was prepared using the same procedure as for Intermediate 1 with tryptamine (2.0 g, 12.5 mmol), 4-trifluoromethoxybenzaldehyde (2.4 g, 1 equiv.) and TFA (1.9 mL, 2 equiv.) to give the title compound (1.6 g, 38%) as a white powder. MP: 68-69° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06043252
Source datasetuspto-grants-2000_03
ORD IDord-7bb4bc6957934fd4a2595c1d5faa9d3e
Source noteuspto-grants-2000_03