Sodium Hydroxide → HCID 178517077, compound

HRID 1637922Notes

Reaction equation

HRID 1637922 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[NH:24]1[CH:28]=[C:27]([C:29]2[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=2)[N:26]=[CH:25]1.[OH-].[Na+]>CN(C=O)C.CO>[NH:24]1[CH:28]=[C:27]([C:29]2[CH:35]=[CH:34][C:32]([NH:33]/[C:13](=[C:6]3\[C:5](=[O:23])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[CH:10][CH:11]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:31][CH:30]=2)[N:26]=[CH:25]1

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinoneHCID 178507418HCID 178507418, compound

Product 1

HCID 178517077HCID 178517077, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone and 1.5 equivalents of 4-(1H-imidazol-4-yl)-aniline in DMF followed by treatment with 1N sodium hydroxide solution in MeOH.

Sources & evidence

ORD record
ord-71a1e3b92ebc48878de8b9a6e3dfcd05
Source dataset
uspto-grants-2000_03
Patent number
US06043254

Reaction notes

Loading…