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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1637923Generated: November 2, 2026

Sodium Hydroxide → HCID 178481637, compound

https://huagongshe.com/reaction/1637923

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant5-Amino-1,3-dihydro-1-methyl-2H-benzimidazol-2-oneHCID 15508437—
Reactant1-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinoneHCID 54237888—
SolventMethanolHCID 887—
SolventDimethylformamideHCID 6228—
ProductHCID 178481637HCID 178481637—

Reaction Steps

Prepared from 1-acetyl-3-{1-ethoxy-1-phenylmethylidene}-2-indolinone and 3 equivalents of crude 5-amino-1-methyl-2-oxo-2,3-dihydro-1H-benzimidazole in DMF followed by treatment with 1N sodium hydroxide solution in MeOH.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06043254
Source datasetuspto-grants-2000_03
ORD IDord-192519ceeafe40658ff16084c6c9f95a
Source noteuspto-grants-2000_03