6-Aminoquinoline → HCID 178517072, compound

HRID 1637925Notes

Reaction equation

HRID 1637925 reaction equation
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13](OCC)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[NH2:24][C:25]1[CH:26]=[C:27]2[C:32](=[CH:33][CH:34]=1)[N:31]=[CH:30][CH:29]=[CH:28]2.[OH-].[Na+]>CN(C=O)C.CO>[N:31]1[C:32]2[C:27](=[CH:26][C:25]([NH:24]/[C:13](=[C:6]3\[C:5](=[O:23])[NH:4][C:12]4[C:7]\3=[CH:8][CH:9]=[CH:10][CH:11]=4)/[C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:34][CH:33]=2)[CH:28]=[CH:29][CH:30]=1

Participants

6

Reactant 3

HCID 113736-AminoquinolineHCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

Product 1

HCID 178517072HCID 178517072, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Prepared from 1-acetyl-3-{1-ethoxy-1-phenylmethylidene}-2-indolinone and 3 equivalents of 6-amino-quinoline in DMF followed by treatment with 1N sodium hydroxide solution in MeOH.

Sources & evidence

ORD record
ord-e547f76bad8c4537b866b0adf03ab7b2
Source dataset
uspto-grants-2000_03
Patent number
US06043254

Reaction notes

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