HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-(p-nitrophenyl)thiazole → 2-Amino-4-(4-aminophenyl)thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-(p-nitrophenyl)thiazole | HCID 16420 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Amino-4-(4-aminophenyl)thiazole | HCID 605564 | — |
Reaction Steps
Prepared by 2 hours' hydrogenation of 2-amino-4-(4-nitro-phenyl)-thiazole (melting point: 287-291° C.; prepared from ω-bromo-4-nitro-acetophenone and thiourea) in DMF on palladium/charcoal (10%) at 20° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043254 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-be4ae694ac25499fa8fc165414f891c9 |
| Source note | uspto-grants-2000_03 |