HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 54527564, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 5-(3-nitrobenzylidene)imidazolidine-2,4-dione | HCID 377825 | — |
| Reactant | 2-Amino-4-(4-aminophenyl)thiazole | HCID 605564 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54527564 | HCID 54527564 | — |
Reaction Steps
2.3 g (10 mmol) of crude 3-nitro-benzylidene-hydantoin, melting point 280-284° C., (prepared as described in Example 6 in (a)) are hydrogenated in 60 ml of DMF and 40 ml EtOH on 2 g of Raney nickel for 36 hours at 20° C. and 3.5 bar. It is filtered over kieselguhr and the filtrate is evaporated down in vacuo. The evaporation residue is crystallised with ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06043254 |
| Source dataset | uspto-grants-2000_03 |
| ORD ID | ord-868b03d787424b74b9f08e5b99c7e1e2 |
| Source note | uspto-grants-2000_03 |