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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1637935Generated: October 31, 2026

Methyl iodide → 1-methyl-4-(4-nitrophenyl)-1H-imidazole

https://huagongshe.com/reaction/1637935

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium tertbutoxideHCID 50987170—
ReactantHCID 178418805HCID 178418805—
SolventDimethyl SulfoxideHCID 679—
Product1-methyl-4-(4-nitrophenyl)-1H-imidazoleHCID 18800474—

Reaction Steps

Prepared by reacting 4-(4-nitro-phenyl)-imidazole in DMSO with potassium-tert.butoxide at 0° C. and then with methyliodide at 20-25° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06043254
Source datasetuspto-grants-2000_03
ORD IDord-d0f1bbea951146c8a5e26bb695dd3931
Source noteuspto-grants-2000_03