Hydroxyamine hydrochloride → 4-Oximino-3-propyl-tetrahydrothiopyran

HRID 1638142Notes

Reaction equation

[CH2:1]([CH:4]1[C:9](=O)[CH2:8][CH2:7][S:6][CH2:5]1)[CH2:2][CH3:3].Cl.[NH2:12][OH:13]>>[N:12](=[C:9]1[CH2:8][CH2:7][S:6][CH2:5][CH:4]1[CH2:1][CH2:2][CH3:3])[OH:13]

Participants

Reactant 2

HCID 443297Hydroxyamine hydrochloride

HCID 110409693-Propyl-tetrahydrothiopyran-4-one

Product 1

HCID 867552674-Oximino-3-propyl-tetrahydrothiopyran

Procedure

Employing the procedure described in Example 2, step A, 3-propyl-tetrahydrothiopyran-4-one was reacted with hydroxylamine hydrochloride to form 4-oximino-3-propyl-tetrahydrothiopyran and was used directly in the subsequent reaction.

Sources & evidence

ORD record: ord-3268eb08cd1b42ef8f02f9a0c06f608a
Source dataset: uspto-grants-2000_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06043358

Reaction notes

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