Hydrochloric Acid → HCID 14391421, compound

HRID 1638240Notes

Reaction equation

[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10]([C:12]1[CH:22]=[CH:21][C:15]([O:16][CH2:17][C:18](O)=[O:19])=[CH:14][CH:13]=1)=[O:11].S(Cl)([Cl:25])=O.Cl.S(=O)(O)O>O1CCOCC1>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10]([C:12]1[CH:22]=[CH:21][C:15]([O:16][CH2:17][C:18]([Cl:25])=[O:19])=[CH:14][CH:13]=1)=[O:11]

Participants

Conditions

Temperature: 80 °C

Procedure

A mixture of 3.54 g of 4-(2,3-dichlorophenyl-carbamoyl)-phenoxyacetic acid, 3.57 g of thionyl chloride and 30 ml of dioxane was stirred at a temperature of 80° C. for 4 hours. An excess amount of thionyl chloride and dissolved hydrochloric acid gas, sulfurous acid gas and dioxane were distilled off by a rotary evaporator to obtain 4-(2,3-dichlorophenyl-carbamoyl)-phenoxyacetyl chloride as the residue after distillation.

Workup

distillationwere distilled off by a rotary evaporator

Sources & evidence

ORD record: ord-8fb3ae30ca0741af9d11c658e1ba415a
Source dataset: uspto-grants-1989_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04878942

Reaction notes

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