Ethanolamine → HCID 178511456, compound

Participants

Reaction Steps

To a suspension of 2-(2-hydroxyphenyl)-N-(1H-tetrazole-5-yl)-4-thiazolecarboxamide (200 mg) in dry methanol (15 ml) was added 2-aminoethanol (0.045 ml) and allowed to dissolve. After allowing for additional 30 minutes at room temperature, the produced solids was filtered and washed with dry ether and then with dry acetone. The filtrate was concentrated and the residue was crystallized by adding dry ether. These crystals wrere combined and dried to give white solids of 2-(2-hydroxyphenyl)-N-(1H-tetrazole-5-yl)-4-thiazolecarboxamide 2-aminoethanol salt (130 mg, 54%).

Provenance & Evidence