Hexane → HCID 53905861, compound

HRID 1638451Notes

Reaction equation

HRID 1638451 reaction equation
CCCCCC.C(OCC)(=O)C.[F:13][C:14]1[CH:15]=[C:16]([N:20]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH2:22][C:21]2=[O:29])[CH:17]=[CH:18][CH:19]=1>CCOCC.CCCCC>[F:13][C:14]1[CH:15]=[C:16]([N:20]2[C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[C:22](=[CH:16][N:20]([CH3:28])[CH3:21])[C:21]2=[O:29])[CH:17]=[CH:18][CH:19]=1

Participants

5

Reactant 3

HCID 8058Hexane2×HCID 8857Ethyl Acetate2×HCID 13339540HCID 13339540, compound

Product 1

HCID 53905861HCID 53905861, compound

Reagents, catalysts & solvents 1

HCID 21877078Diethylether pentaneSolvent

Procedure

By the procedure of Example Al, but using 13:7 hexane:ethyl acetate and then 3:7 hexane:ethyl acetate as eluant and ether/pentane for crystallization, 1-(3-fluorophenyl)-2(1H,3H)-indolone (0.80 g, 3.5 mmoles) was converted to title product, 0.53 g, m.p. 87°-88.5°.

Sources & evidence

ORD record
ord-dfb009257c59488bbec19fc7d28fe725
Source dataset
uspto-grants-1989_11
Patent number
US04879391

Reaction notes

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