Potassium Carbonate → HCID 14652424, compound

HRID 1638725Notes

Reaction equation

HRID 1638725 reaction equation
[S:1]1[CH2:5][CH2:4][CH2:3][CH:2]1[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[OH:12].[CH2:13]([O:15][P:16](Cl)([O:18][CH2:19][CH3:20])=[S:17])[CH3:14].C(=O)([O-])[O-].[K+].[K+]>C(C(C)=O)C>[P:16](=[S:17])([O:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[CH:2]1[CH2:3][CH2:4][CH2:5][S:1]1)([O:18][CH2:19][CH3:20])[O:15][CH2:13][CH3:14]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 17305O,O-diethyl phosphorochloridothioateHCID 14421231HCID 14421231, compound

Product 1

HCID 14652424HCID 14652424, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

A mixture of 3 g. of 2-(tetrahydro-2-thienyl) phenol, 4 g. of diethylchlorothiophosphate, 50 ml. of methyl ethyl ketone and 10 g. of anhydrous potassium carbonate was refluxed for 5 hours. Thereafter, the solids were recovered by filtration and the solvent was removed. The residue was treated with ether and water resulting in the formation of a two-layer liquid. The water layer was removed and the ether layer was washed twice with water. The ether layer resulting therefrom was dried over magnesium sulfate and the solvent removed.

Workup

  1. additionA mixture of 3 g
  2. filtrationThereafter, the solids were recovered by filtration
  3. customthe solvent was removed
  4. additionThe residue was treated with ether and water resulting in the formation of a two-layer liquid
  5. customThe water layer was removed
  6. washthe ether layer was washed twice with water
  7. customThe ether layer resulting
  8. dry with materialtherefrom was dried over magnesium sulfate
  9. customthe solvent removed

Sources & evidence

ORD record
ord-31412756cdd94d0a83c1975f6a91d4d0
Source dataset
uspto-grants-1989_11
Patent number
US04880828

Reaction notes

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