HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 7-Chloro-2,3-dihydro-4-isocyanato-2-methylbenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | 7-Chloro-2-methyl-2,3-dihydrobenzofuran-4-amine | HCID 53671460 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 7-Chloro-2,3-dihydro-4-isocyanato-2-methylbenzofuran | HCID 53718402 | — |
Reaction Steps
6.07 g of triethylamine was added to a mixture of 9.18 g of 32A, 11.87 g of trichloromethyl chloroformate and 250 mL of dioxane, and the mixture was refluxed for 6 hours. The mixture was cooled, filtered, and the filtrate was stripped of solvent, to give 7-chloro-2,3-dihydro-4-isocyanato-2-methylbenzofuran (34A), as a brown liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04881967 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-c597f652f8d34bf894b7e9fdffa0b69f |
| Source note | uspto-grants-1989_11 |